Uri Tabori is paediatric oncologist at SickKids and is a professor in the departments of Medical Biophysics, Institute of Medical Science and Paediatrics, University of Toronto.Based on his clinical background and expertise, his research focuses on translational aspects of cancer originating from patients need, through basic discoveries and clinical trials to changes in how society is managing specific cancers. Specifically, Uri focuses on the development of systems for early detection, intervention and therapeutics in individuals highly predisposed to developing brain tumours.Uri leads the International RRD Consortium (IRRDC) which is supporting patients and families in diagnosis, management and therapies in 45 countries. The consortium is running international clinical trials for children with hypermutant cancers with immune checkpoint inhibitors and combinations. Uri is also developing animal models and companion biomarker designed for immunotherapy therapeutics.
Uri also co-leads the paediatric low grade glioma (PLGG) taskforce which uncovers novel alterations in this most common brain tumour in children and offers targeted therapies and trials. He is responsible for the development of companion biomarkers to these trials.
Uri has been the recipient of numerous awards, including the Canadian Cancer Society’s Bernard and Francine Dorval Prize in 2016 and the Early Researcher Award from the Ontario Ministry of Development in Innovation in 2014. He also and holds the Garron Family Chair appointment in Childhood Cancer Research.